Subchronic toxicological study of two artemisinin derivatives in dogs.

The objective of our study was to profile and compare the systematic changes between orally administered artesunate and intramuscularly injected artemether at a low dose over a 3-month period (92 consecutive days) in dogs. Intramuscular administration of 6 mg kg-1 artemether induced a decreased red...

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Bibliographic Details
Main Authors: Ji-ye Yin, He-mei Wang, Quan-jun Wang, Yan-sheng Dong, Gang Han, Yong-biao Guan, Ke-yong Zhao, Wen-sheng Qu, Ye Yuan, Xiao-xin Gao, Shu-fang Jing, Ri-gao Ding
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3989207?pdf=render