Axonal degeneration in an in vitro model of ischemic white matter injury

Ischemic white matter injuries underlie cognitive decline in the elderly and vascular dementia. Ischemia in the subcortical white matter is caused by chronic reduction of blood flow due to narrowing of small arterioles. However, it remains unclear how chronic ischemia leads to white matter pathology...

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Bibliographic Details
Main Authors: Yuexian Cui, Xuelian Jin, Dong-Joo Choi, Jun Young Choi, Hyung Soon Kim, Dong Hoon Hwang, Byung Gon Kim
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S096999611930347X