Antitumor action of an aminochromene derivative on human - derived lung adenocarcinoma xenograft model

Antitumor action of an aminochromene derivative on human - derived lung adenocarcinoma xenograft model

Aim. To study antitumor and anti - metastatic action of AKh-554, 2-Aminium-7-(Diethylamino)-4-(4-Metoxibenzo[d][1,3]dioxol-5-yl)-4H-chromene-3-carbonytril N-Acetylamino - ethanoate, on in vivo model of lung adenocarcinoma patient - derived xenograft model. Materials and methods. In 40 immunodeficient...

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Bibliographic Details
Main Authors: E. A. Samishina, M. O. Dudina, E. V. Blinova, I. R. Suslova, O. N. Deryabina, D. S. Blinov, P. N. Zhdanov
Format: Article
Language:Russian
Published: Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University) 2019-06-01
Series:Сеченовский вестник
Subjects:
akh-554
xenograft
lung adenocarcinoma
antitumor effect
mechanism of action
apoptosis
markers of tumor progression
Online Access:https://www.sechenovmedj.com/jour/article/view/99

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https://www.sechenovmedj.com/jour/article/view/99

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