Different Time Courses of Mono- and Bi-Liganded Bursts of Channel Openings of Adult nAChR Molecules Formed by the Reactions of Transmembrane Regions

Different Time Courses of Mono- and Bi-Liganded Bursts of Channel Openings of Adult nAChR Molecules Formed by the Reactions of Transmembrane Regions

We recorded transmembrane currents through single nicotinic acetylcholine receptors (nAChRs) in cell-attached patches at high temporal resolutions from cultured and transiently transfected HEK 293 cells. Receptor activation was elicited by acetylcholine (ACh) or epibatidine (Ebd) at concentrations r...

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Bibliographic Details
Main Authors: Dmitrij Ljaschenko, Martin Pauli, Achmed Mrestani, Josef Dudel, Manfred Heckmann
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Cells
Subjects:
acetylcholine
burst
channel
endplate
kinetics
receptor
Online Access:https://www.mdpi.com/2073-4409/13/24/2079

Internet

https://www.mdpi.com/2073-4409/13/24/2079

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