Coding joint: kappa-deleting recombination excision circle ratio and B cell activating factor level: predicting juvenile dermatomyositis rituximab response, a proof-of-concept study

Coding joint: kappa-deleting recombination excision circle ratio and B cell activating factor level: predicting juvenile dermatomyositis rituximab response, a proof-of-concept study

Abstract Background This pilot study’s primary aim was to determine if oligoclonal B cell expansion in children with Juvenile Dermatomyositis (JDM) predicts response to Rituximab therapy. We evaluated: (1) tissue B cell depletion efficacy by measuring the ratio of Coding joint (CJ) to Kappa-deleting...

Full description

Bibliographic Details
Main Authors: Elisa Ochfeld, Victoria Hans, Wil Marin, Najah Ahsan, Gabrielle Morgan, Lauren M. Pachman, Amer Khojah
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Rheumatology
Subjects:
Juvenile dermatomyositis
Rituximab response
BAFF level
KREC evaluation
Online Access:https://doi.org/10.1186/s41927-022-00265-z

Internet

https://doi.org/10.1186/s41927-022-00265-z

Similar Items