Self-organization of conducting pathways explains electrical wave propagation in cardiac tissues with high fraction of non-conducting cells.

Cardiac fibrosis occurs in many forms of heart disease and is considered to be one of the main arrhythmogenic factors. Regions with a high density of fibroblasts are likely to cause blocks of wave propagation that give rise to dangerous cardiac arrhythmias. Therefore, studies of the wave propagation...

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Bibliographic Details
Main Authors: Nina Kudryashova, Aygul Nizamieva, Valeriya Tsvelaya, Alexander V Panfilov, Konstantin I Agladze
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-03-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1006597