Distinct mechanisms drive sequential internalization and degradation of GABAARs during global ischemia and reperfusion injury
Summary: Synaptic inhibition is critical for controlling neuronal excitability and function. During global cerebral ischemia (GCI), inhibitory synapses are rapidly eliminated, causing hyper-excitability which contributes to cell-death and the pathophysiology of disease. Sequential disassembly of inh...
| Main Authors: | , , , , , , , |
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| פורמט: | Article |
| שפה: | English |
| יצא לאור: |
Elsevier
2023-10-01
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| סדרה: | iScience |
| נושאים: | |
| גישה מקוונת: | http://www.sciencedirect.com/science/article/pii/S2589004223021387 |