Harnessing Tumor Necrosis Factor Alpha to Achieve Effective Cancer Immunotherapy

Harnessing Tumor Necrosis Factor Alpha to Achieve Effective Cancer Immunotherapy

Tumor necrosis factor alpha (TNFα) is a pleiotropic cytokine known to have contradictory roles in oncoimmunology. Indeed, TNFα has a central role in the onset of the immune response, inducing both activation and the effector function of macrophages, dendritic cells, natural killer (NK) cells, and B...

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Bibliographic Details
Main Authors: María Florencia Mercogliano, Sofía Bruni, Florencia Mauro, Patricia Virginia Elizalde, Roxana Schillaci
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
TNFα
immunotherapy
adoptive cell therapy
monoclonal antibody
immune checkpoint inhibitor
cancer
Online Access:https://www.mdpi.com/2072-6694/13/3/564

Internet

https://www.mdpi.com/2072-6694/13/3/564

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