Importin-8 Modulates Division of Apical Progenitors, Dendritogenesis and Tangential Migration During Development of Mouse Cortex

Importin-8 Modulates Division of Apical Progenitors, Dendritogenesis and Tangential Migration During Development of Mouse Cortex

The building of the brain is a multistep process that requires the coordinate expression of thousands of genes and an intense nucleocytoplasmic transport of RNA and proteins. This transport is mediated by karyopherins that comprise importins and exportins. Here, we investigated the role of the ß-imp...

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Bibliographic Details
Main Authors: Gerry Nganou, Carla G. Silva, Ivan Gladwyn-Ng, Dominique Engel, Bernard Coumans, Antonio V. Delgado-Escueta, Miyabi Tanaka, Laurent Nguyen, Thierry Grisar, Laurence de Nijs, Bernard Lakaye
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Molecular Neuroscience
Subjects:
karyopherin
importin-8
corticogenesis
radial migration
tangential migration
dendritogenesis
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00234/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2018.00234/full

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