Expression of pH-Sensitive TRPC4 in Common Skin Tumors

Expression of pH-Sensitive TRPC4 in Common Skin Tumors

TRPCs (transient receptor potential classical or cation channels) play a crucial role in tumor biology, especially in the Ca<sup>2+</sup> homeostasis in cancer cells. TRPC4 is a pH-sensitive member of this family of proteins. As solid tumors exhibit an inversed pH-gradient with lowered e...

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Bibliographic Details
Main Authors: Bernadett Kurz, Hannah Philine Michael, Antonia Förch, Susanne Wallner, Florian Zeman, Sonja-Maria Decking, Ines Ugele, Constantin Hintschich, Frank Haubner, Tobias Ettl, Kathrin Renner, Christoph Brochhausen, Stephan Schreml
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
TRPC4
skin tumors
melanoma
squamous cell carcinoma
basal cell carcinoma
Online Access:https://www.mdpi.com/1422-0067/24/2/1037

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https://www.mdpi.com/1422-0067/24/2/1037

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