3D-QSAR models to predict anti-cancer activity on a series of protein P38 MAP kinase inhibitors

Protein kinases are essential components of various signaling pathways and represent attractive targets for therapeutic interventions. Kinase inhibitors are currently used to treat malignant tumors, as well as autoimmune diseases, due to their involvement in immune cell signaling. In this study, thr...

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Bibliographic Details
Main Authors: El Ghalia Hadaji, Mohamed Bourass, Abdelkarim Ouammou, Mohammed Bouachrine
Format: Article
Language:English
Published: Taylor & Francis Group 2017-05-01
Series:Journal of Taibah University for Science
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1658365516300371