miR-6869-5p Transported by Plasma Extracellular Vesicles Mediates Renal Tubule Injury and Renin-Angiotensin System Activation in Obesity

Obesity increases the risk of other diseases, including kidney disease. Local renal tubular renin-angiotensin system (RAS) activation may play a role in obesity-associated kidney disease. Extracellular vehicles (EVs) transmit necessary information in obesity and cause remote organ damage, but the me...

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Bibliographic Details
Main Authors: Huan-Huan Liu, Xia-Qing Li, Jin-Feng Liu, Shuang Cui, Han Liu, Bo Hu, Si-Bo Huang, Li Wang, Wah Yang, Cun-Chuan Wang, Yu Meng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.725598/full