Benefits and Harms of Standard Versus Reduced‐Dose Direct Oral Anticoagulant Therapy for Older Adults With Multiple Morbidities and Atrial Fibrillation

Benefits and Harms of Standard Versus Reduced‐Dose Direct Oral Anticoagulant Therapy for Older Adults With Multiple Morbidities and Atrial Fibrillation

Background Dose reduction of direct oral anticoagulant (DOAC) medications is inconsistently applied to older adults with multiple morbidities, potentially due to perceived harms and unknown benefits of standard dosing. Methods and Results Using 2013 to 2017 US Medicare claims linked to Minimum Data...

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Bibliographic Details
Main Authors: Kaleen N. Hayes, Tingting Zhang, Dae Hyun Kim, Lori A. Daiello, Yoojin Lee, Douglas P. Kiel, Sarah D. Berry, Andrew R. Zullo
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
Editorials
aging
atrial fibrillation
comparative effectiveness research
factor Xa inhibitors
frail elderly
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.122.029865

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.122.029865

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