Synthesis and biological evaluation of anthracene-9,10 dione derivatives as CK2 inhibitors

Human protein kinase CK2 is an important target for the development of anticancer drugs. Many inhibitors were developed in the last few decades, among them emodin, a natural inhibitor with anthracene-9,10-dione backbone. In this work the inhibitory activity of another natural compound endocrocin hav...

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Bibliographic Details
Main Authors: Priscila López-Rojas, Samer Haidar, Franziska M. Jürgens, Dagmar Aichele, Ángel Amesty, Ana Estévez-Braun, Joachim Jose
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715623002369