Establishing a Herpesvirus Quiescent Infection in Differentiated Human Dorsal Root Ganglion Neuronal Cell Line Mediated by Micro-RNA Overexpression

Establishing a Herpesvirus Quiescent Infection in Differentiated Human Dorsal Root Ganglion Neuronal Cell Line Mediated by Micro-RNA Overexpression

HSV-1 is a neurotropic pathogen associated with severe encephalitis, excruciating orofacial sensation, and other chronic neuropathic complications. After the acute infection, the virus may establish a lifelong latency in the neurons of trigeminal ganglia (TG) and other sensory and autonomic ganglia,...

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Bibliographic Details
Main Authors: Yu-Chih Chen, Hedong Li, Miguel Martin-Caraballo, Shaochung Victor Hsia
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Pathogens
Subjects:
host–virus interaction
herpesvirus
microRNA
dorsal root ganglion
latency
reactivation
Online Access:https://www.mdpi.com/2076-0817/11/7/803

Internet

https://www.mdpi.com/2076-0817/11/7/803

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