Functionalized calcium phosphate nanoparticles to direct osteoprotegerin to bone lesion sites in a medaka (Oryzias latipes) osteoporosis model

Functionalized calcium phosphate nanoparticles to direct osteoprotegerin to bone lesion sites in a medaka (Oryzias latipes) osteoporosis model

Calcium phosphate (CaP) is the inorganic part of hard tissues, such as bone, teeth and tendons, and has a high biocompatibility and good biodegradability. Therefore, CaP nanoparticles functionalized with DNA encoding bone anabolic factors are promising carrier-systems for future therapeutic developm...

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Bibliographic Details
Main Authors: Nurgul Imangali, Viktoriya Sokolova, Kathrin Kostka, Matthias Epple, Christoph Winkler
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Endocrinology
Subjects:
osteoporosis
nanoparticles
bone resorption
Rankl
osteoprotegerin
OPG
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1101758/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1101758/full

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