Soy Isoflavone Genistein Impedes Cancer Stemness and Mesenchymal Transition in Head and Neck Cancer through Activating miR-34a/RTCB Axis

Soy Isoflavone Genistein Impedes Cancer Stemness and Mesenchymal Transition in Head and Neck Cancer through Activating miR-34a/RTCB Axis

Genistein, a soy-derived phytoestrogen, has been shown to exhibit anti-neoplastic activities in various cancers. Nevertheless, its effects on the elimination of tumor-initiating cells of head and neck cancer (HNC-TICs) remain unclear. Here, we investigated the inhibitory effect of genistein on HNC-T...

Full description

Bibliographic Details
Main Authors: Pei-Ling Hsieh, Yi-Wen Liao, Chang-Wei Hsieh, Pei-Ni Chen, Cheng-Chia Yu
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Nutrients
Subjects:
cancer stemness
genistein
head and neck cancer
Microrna-34a
RTCB
Online Access:https://www.mdpi.com/2072-6643/12/7/1924

Internet

https://www.mdpi.com/2072-6643/12/7/1924

Similar Items