Evaluating the prognostic performance of a polygenic risk score for breast cancer risk stratification

Abstract Background Polygenic risk scores (PRS) could potentially improve breast cancer screening recommendations. Before a PRS can be considered for implementation, it needs rigorous evaluation, using performance measures that can inform about its future clinical value. Objectives To evaluate the p...

Full description

Bibliographic Details
Main Authors: Maria Olsen, Krista Fischer, Patrick M. Bossuyt, Els Goetghebeur
Format: Article
Language:English
Published: BMC 2021-12-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-021-08937-8