Elevated monocyte HLA-DR in pediatric secondary hemophagocytic lymphohistiocytosis: a retrospective study

Elevated monocyte HLA-DR in pediatric secondary hemophagocytic lymphohistiocytosis: a retrospective study

IntroductionHemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition, and its diagnosis may be challenging. In particular, some cases show close similarities to sepsis (fever, organ failure, and high ferritin), but their treatment, while urgent, differ: prompt broad-spectrum antibiot...

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Bibliographic Details
Main Authors: Sylvain Raimbault, Guillaume Monneret, Morgane Gossez, Fabienne Venet, Alexandre Belot, Franck Zekre, Solene Remy, Etienne Javouhey
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
hemophagocytic lymphohistiocytosis
monocyte HLA-DR
macrophage activation syndrome
lymphocyte activation
cytokine storm
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1286749/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1286749/full

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