A modified apical resection model with high accuracy and reproducibility in neonatal mouse and rat hearts

Abstract Neonatal mouse heart can regenerate after left ventricle (LV) apical resection (AR). Since current AR rodent method is accomplished by resecting LV apex until exposure of LV chamber, it is relatively difficult to operate reproducibly. We aimed to develop a modified AR method with high accur...

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Bibliographic Details
Main Authors: Yihua Bei, Chen Chen, Xuejiao Hua, Mingming Yin, Xiangmin Meng, Zhenzhen Huang, Weitong Qi, Zhuhua Su, Chang Liu, H. Immo Lehmann, Guoping Li, Yu Huang, Junjie Xiao
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-023-00284-5