A Computational Approach for Modeling the Allele Frequency Spectrum of Populations with Arbitrarily Varying Size

The allele frequency spectrum (AFS), or site frequency spectrum, is commonly used to summarize the genomic polymorphism pattern of a sample, which is informative for inferring population history and detecting natural selection. In 2013, Chen and Chen developed a method for analytically deriving the...

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Autore principale: Hua Chen
Natura: Articolo
Lingua:English
Pubblicazione: Oxford University Press 2019-12-01
Serie:Genomics, Proteomics & Bioinformatics
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Accesso online:http://www.sciencedirect.com/science/article/pii/S167202292030022X