In vivo evaluation of a recombinant N-acylhomoserine lactonase formulated in a hydrogel using a murine model infected with MDR Pseudomonas aeruginosa clinical isolate, CCASUP2

In vivo evaluation of a recombinant N-acylhomoserine lactonase formulated in a hydrogel using a murine model infected with MDR Pseudomonas aeruginosa clinical isolate, CCASUP2

Abstract Failure in the treatment of P. aeruginosa, due to its broad spectrum of resistance, has been associated with increased patient mortality. One alternative approach for infection control is quorum quenching which was found to decrease virulence of such pathogen. In this study, the efficiency...

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Bibliographic Details
Main Authors: Masarra M. Sakr, Walid F. Elkhatib, Khaled M. Aboshanab, Eman M. Mantawy, Mahmoud A. Yassien, Nadia A. Hassouna
Format: Article
Language:English
Published: SpringerOpen 2021-07-01
Series:AMB Express
Subjects:
Quorum quenching
N-acylhomoserine lactonase
P. aeruginosa
Burn infection
Online Access:https://doi.org/10.1186/s13568-021-01269-7

Internet

https://doi.org/10.1186/s13568-021-01269-7

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