The mechanism underlying correlation of particulate matter-induced ferroptosis with inflammasome activation and iron accumulation in macrophages

Abstract Particulate matter (PM) is a global environmental hazard, which affects human health through free radical production, cell death induction, and immune responses. PM activates inflammasomes leading to excessive inflammatory responses and induces ferroptosis, a type of cell death. Despite ong...

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Bibliographic Details
Main Authors: Minkyung Park, Sujeong Park, Yumin Choi, Young-Lai Cho, Min Jeong Kim, Young-Jun Park, Su Wol Chung, Heedoo Lee, Seon-Jin Lee
Format: Article
Language:English
Published: Nature Publishing Group 2024-03-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-01874-y