Catalytic mechanism investigation of lysine-specific demethylase 1 (LSD1): a computational study.

Catalytic mechanism investigation of lysine-specific demethylase 1 (LSD1): a computational study.

Lysine-specific demethylase 1 (LSD1), the first identified histone demethylase, is a flavin-dependent amine oxidase which specifically demethylates mono- or dimethylated H3K4 and H3K9 via a redox process. It participates in a broad spectrum of biological processes and is of high importance in cell p...

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Bibliographic Details
Main Authors: Xiangqian Kong, Sisheng Ouyang, Zhongjie Liang, Junyan Lu, Liang Chen, Bairong Shen, Donghai Li, Mingyue Zheng, Keqin Kathy Li, Cheng Luo, Hualiang Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3184146?pdf=render

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http://europepmc.org/articles/PMC3184146?pdf=render

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