Interleukin-1β Modulation of the Mechanobiology of Primary Human Pulmonary Fibroblasts: Potential Implications in Lung Repair

Interleukin-1β Modulation of the Mechanobiology of Primary Human Pulmonary Fibroblasts: Potential Implications in Lung Repair

Pro-inflammatory cytokines like interleukin-1β (IL-1β) are upregulated during early responses to tissue damage and are expected to transiently compromise the mechanical microenvironment. Fibroblasts are key regulators of tissue mechanics in the lungs and other organs. However, the effects of IL-1β o...

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Bibliographic Details
Main Authors: Marta Gabasa, Marselina Arshakyan, Alejandro Llorente, Lourdes Chuliá-Peris, Irina Pavelescu, Antoni Xaubet, Javier Pereda, Jordi Alcaraz
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
IL-1β
pulmonary fibroblasts
repair
cell mechanics
collagen
MMPs
Online Access:https://www.mdpi.com/1422-0067/21/22/8417

Internet

https://www.mdpi.com/1422-0067/21/22/8417

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