Pirenperone relieves the symptoms of fragile X syndrome in Fmr1 knockout mice

Abstract Fragile X syndrome (FXS) is a neurodevelopmental disorder that is caused by the loss of Fragile X-linked mental retardation protein (FMRP), an RNA binding protein that can bind and recognize different RNA structures and regulate the target mRNAs’ translation involved in neuronal synaptic pl...

Full description

Bibliographic Details
Main Authors: Yujeong Kim, Se Jin Jeon, Edson Luck Gonzales, Dongpil Shin, Chilly Gay Remonde, TaeJin Ahn, Chan Young Shin
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-25582-8