Formation of Sterically Congested C−N Bonds by Electrochemical Reductive Coupling of Amines and α‐Bromocarboxamides

Formation of Sterically Congested C−N Bonds by Electrochemical Reductive Coupling of Amines and α‐Bromocarboxamides

Abstract Nucleophilic substitution of α‐bromocarboxamide with amines have been demonstrated to synthesize sterically congested C−N bonds. Electrochemical reductive coupling is an efficient route to access hindered amino acid derivatives possessing a quaternary carbon center with excellent yields und...

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Bibliographic Details
Main Authors: Dr. Titli Ghosh, Hazuki Kaizawa, Shohei Funato, Dr. M. Azadur Rahman, Dr. Norihiko Sasaki, Prof. Toshiki Nokami, Prof. Manabu Abe, Prof. Takashi Nishikata
Format: Article
Language:English
Published: Wiley-VCH 2024-03-01
Series:ChemElectroChem
Subjects:
amination
electrochemical reduction
tertiary amine
α-bromocarboxamide
amino acid
Online Access:https://doi.org/10.1002/celc.202300636

Internet

https://doi.org/10.1002/celc.202300636

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