Potential application of bisoprolol derivative compounds as antihypertensive drugs: synthesis and in silico study

Two bisoprolol derivatives, N-acetyl bisoprolol and N-formyl bisoprolol, belonging to the beta-blocker class of antihypertensive drugs, were synthesized using acetylation and formylation reactions. The yields of the reactions were determined to be 32.40% for N-acetyl bisoprolol and 20.20% for N-form...

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Bibliographic Details
Main Authors: Ni Putu Sani Oktaviani, Atthar Luqman Ivansyah, Muhammad Yogi Saputra, Nurrahmi Handayani, Nurdiani Fadylla, Deana Wahyuningrum
Format: Article
Language:English
Published: The Royal Society 2023-12-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.231112