Clinical Significance and Regulation of ERK5 Expression and Function in Cancer

Clinical Significance and Regulation of ERK5 Expression and Function in Cancer

Extracellular signal-regulated kinase 5 (ERK5) is a unique kinase among MAPKs family members, given its large structure characterized by the presence of a unique C-terminal domain. Despite increasing data demonstrating the relevance of the ERK5 pathway in the growth, survival, and differentiation of...

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Bibliographic Details
Main Authors: Matilde Monti, Jacopo Celli, Francesco Missale, Francesca Cersosimo, Mariapia Russo, Elisa Belloni, Anna Di Matteo, Silvia Lonardi, William Vermi, Claudia Ghigna, Emanuele Giurisato
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cancers
Subjects:
ERK5
cancer
alternative splicing
prognostic markers
tumor microenvironment
cancer-stem cells
Online Access:https://www.mdpi.com/2072-6694/14/2/348

Internet

https://www.mdpi.com/2072-6694/14/2/348

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