Proteoglycan Dysfunction: A Common Link Between Intervertebral Disc Degeneration and Skeletal Dysplasia

Proteoglycans through their sulfated glycosaminoglycans regulate cell-matrix signaling during tissue development, regeneration, and degeneration processes. Large extracellular proteoglycans such as aggrecan, versican, and perlecan are especially important for the structural integrity of the interver...

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Bibliographic Details
Main Authors: Kimheak Sao, Makarand V. Risbud
Format: Article
Language:English
Published: Korean Spinal Neurosurgery Society 2024-03-01
Series:Neurospine
Subjects:
Online Access:http://www.e-neurospine.org/upload/pdf/ns-2347342-671.pdf