Brain–Bone Crosstalk in a Murine Polytrauma Model Promotes Bone Remodeling but Impairs Neuromotor Recovery and Anxiety-Related Behavior

Brain–Bone Crosstalk in a Murine Polytrauma Model Promotes Bone Remodeling but Impairs Neuromotor Recovery and Anxiety-Related Behavior

Traumatic brain injury (TBI) and long bone fractures are a common injury pattern in polytrauma patients and modulate each other’s healing process. As only a limited number of studies have investigated both traumatic sites, we tested the hypothesis that brain–bone polytrauma mutually impacts neuro- a...

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Bibliographic Details
Main Authors: Katharina Ritter, Markus Baalmann, Christopher Dolderer, Ulrike Ritz, Michael K. E. Schäfer
Format: Article
Language:English
Published: MDPI AG 2024-06-01
Series:Biomedicines
Subjects:
traumatic brain injury
bone fracture
osteopathology
neuropathology
neuroinflammation
behavior
Online Access:https://www.mdpi.com/2227-9059/12/7/1399

Internet

https://www.mdpi.com/2227-9059/12/7/1399

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