HBZ upregulates myoferlin expression to facilitate HTLV-1 infection.

HBZ upregulates myoferlin expression to facilitate HTLV-1 infection.

The complex retrovirus, human T-cell leukemia virus type 1 (HTLV-1), primarily infects CD4+ T-cells in vivo. Infectious spread within this cell population requires direct contact between virally-infected and target cells. The HTLV-1 accessory protein, HBZ, was recently shown to enhance HTLV-1 infect...

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Bibliographic Details
Main Authors: Nicholas Polakowski, Md Abu Kawsar Sarker, Kimson Hoang, Georgina Boateng, Amanda W Rushing, Wesley Kendle, Claudine Pique, Patrick L Green, Amanda R Panfil, Isabelle Lemasson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011202

Internet

https://doi.org/10.1371/journal.ppat.1011202

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