Pharmacokinetics and Metabolism Study of Deep-Sea-Derived Butyrolactone I in Rats by UHPLC–MS/MS and UHPLC–Q-TOF-MS

Pharmacokinetics and Metabolism Study of Deep-Sea-Derived Butyrolactone I in Rats by UHPLC–MS/MS and UHPLC–Q-TOF-MS

Butyrolactone I (BTL-I) is a butanolide isolated from the deep-sea-derived fungus, <i>Aspergillus</i> sp. It provides a potential new target for the prevention and treatment of food allergies. This study aimed to investigate the metabolic and pharmacokinetic profile of BTL-I in rats. The...

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Bibliographic Details
Main Authors: Liang Wu, Chun-Lan Xie, Xian-Wen Yang, Gang Chen
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Marine Drugs
Subjects:
butyrolactone I
food allergy
metabolism
pharmacokinetics
Online Access:https://www.mdpi.com/1660-3397/20/1/11

Internet

https://www.mdpi.com/1660-3397/20/1/11

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