PyIR: a scalable wrapper for processing billions of immunoglobulin and T cell receptor sequences using IgBLAST

PyIR: a scalable wrapper for processing billions of immunoglobulin and T cell receptor sequences using IgBLAST

Abstract Background Recent advances in DNA sequencing technologies have enabled significant leaps in capacity to generate large volumes of DNA sequence data, which has spurred a rapid growth in the use of bioinformatics as a means of interrogating antibody variable gene repertoires. Common tools use...

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Bibliographic Details
Main Authors: Cinque Soto, Jessica A. Finn, Jordan R. Willis, Samuel B. Day, Robert S. Sinkovits, Taylor Jones, Samuel Schmitz, Jens Meiler, Andre Branchizio, James E. Crowe
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Bioinformatics
Subjects:
Immune repertoires
Antibody
Illumina
CDR3
IgBLAST
Online Access:http://link.springer.com/article/10.1186/s12859-020-03649-5

Internet

http://link.springer.com/article/10.1186/s12859-020-03649-5

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