Population Pharmacokinetics of Cyclosporine in Chinese Pediatric Patients With Acquired Aplastic Anemia

Population Pharmacokinetics of Cyclosporine in Chinese Pediatric Patients With Acquired Aplastic Anemia

Cyclosporine (CsA) is a component of the first-line treatment for acquired aplastic anemia (acquired AA) in pediatric patients. This study aimed to develop a population pharmacokinetic (PK) model of CsA in Chinese pediatric patients with acquired AA to inform individual dosage regimens. A total of 6...

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Bibliographic Details
Main Authors: Xuan Gao, Zhu-Li Bian, Xiao-Hong Qiao, Xiao-Wen Qian, Jun Li, Guo-Mei Shen, Hui Miao, Yi Yu, Jian-Hua Meng, Xiao-Hua Zhu, Jun-Ye Jiang, Jun Le, Ling Yu, Hong-Sheng Wang, Xiao-Wen Zhai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Pharmacology
Subjects:
cyclosporine
population pharmacokinetics
NONMEM
acquired aplastic anemia
pediatric patients
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.933739/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.933739/full

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