Enrichment in conservative amino acid changes among fixed and standing missense variations in slowly evolving proteins

The process of molecular evolution has many elements that are not yet fully understood. Evolutionary rates are known to vary among protein coding and noncoding DNAs, and most of the observed changes in amino acid or nucleotide sequences are assumed to be non-adaptive by the neutral theory of molecul...

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Bibliographic Details
Main Authors: Mingrui Wang, Dapeng Wang, Jun Yu, Shi Huang
Format: Article
Language:English
Published: PeerJ Inc. 2020-09-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/9983.pdf