Ultrasound-targeted microbubble technology facilitates SAHH gene delivery to treat diabetic cardiomyopathy by activating AMPK pathway

Ultrasound-targeted microbubble technology facilitates SAHH gene delivery to treat diabetic cardiomyopathy by activating AMPK pathway

Summary: Diabetic cardiomyopathy (DCM) is a cardiovascular complication with no known cure. In this study, we evaluated the combination of ultrasound-targeted microbubble destruction (UTMD) and cationic microbubbles (CMBs) for cardiac S-adenosyl homocysteine hydrolase (SAHH) gene transfection as pot...

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Bibliographic Details
Main Authors: Xiaohui Guo, Kegong Chen, Lin Ji, Shanjie Wang, Xiangmei Ye, Liang Xu, Leiguang Feng
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Cardiovascular medicine
Biological sciences
Molecular biology
Biotechnology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224000737

Internet

http://www.sciencedirect.com/science/article/pii/S2589004224000737

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