Ultrasound-targeted microbubble technology facilitates SAHH gene delivery to treat diabetic cardiomyopathy by activating AMPK pathway

Ultrasound-targeted microbubble technology facilitates SAHH gene delivery to treat diabetic cardiomyopathy by activating AMPK pathway

Summary: Diabetic cardiomyopathy (DCM) is a cardiovascular complication with no known cure. In this study, we evaluated the combination of ultrasound-targeted microbubble destruction (UTMD) and cationic microbubbles (CMBs) for cardiac S-adenosyl homocysteine hydrolase (SAHH) gene transfection as pot...

Full description

Bibliographic Details
Main Authors:	Xiaohui Guo, Kegong Chen, Lin Ji, Shanjie Wang, Xiangmei Ye, Liang Xu, Leiguang Feng
Format:	Article
Language:	English
Published:	Elsevier 2024-02-01
Series:	iScience
Subjects:	Cardiovascular medicine Biological sciences Molecular biology Biotechnology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004224000737

Similar Items

AMPK is required for recovery from metabolic stress induced by ultrasound microbubble treatment
by: Louis Lo, et al.
Published: (2023-02-01)

Protocol for in vitro sonoporation validation using non-targeted microbubbles for human studies of ultrasound-mediated gene delivery
by: Nisi Zhang, et al.
Published: (2023-12-01)

Introduction to biology and biotechnology /
by: 520377 Vaidyanath, K., et al.
Published: (2009)

Biology and biotechnology : science, applications, and issues /
by: 198786 Kreuzer, Helen, et al.
Published: (2005)

Cardiac-targeted delivery of nuclear receptor RORα via ultrasound targeted microbubble destruction optimizes the benefits of regular dose of melatonin on sepsis-induced cardiomyopathy
by: Shanjie Wang, et al.
Published: (2023-05-01)

Biosafety & biosecurity issues in high-containment laboratories /
by: Samuels, Damon S.
Published: (2010)

Efficient in vitro delivery of Noggin siRNA enhances osteoblastogenesis
by: S. Ghadakzadeh, et al.
Published: (2017-11-01)

Enhanced cell viscosity: A new phenotype associated with lamin A/C alterations
by: Cécile Jebane, et al.
Published: (2023-10-01)

DIRAS3 enhances RNF19B-mediated RAC1 ubiquitination and degradation in non-small-cell lung cancer cells
by: Yingying Wang, et al.
Published: (2023-07-01)

Probing expression of E-selectin using CRISPR-Cas9-mediated tagging with HiBiT in human endothelial cells
by: Lydia Ogrodzinski, et al.
Published: (2023-07-01)

Optimization-based Eukaryotic Genetic Circuit Design (EuGeneCiD) and modeling (EuGeneCiM) tools: Computational approach to synthetic biology
by: Wheaton L. Schroeder, et al.
Published: (2021-09-01)

Biotechnological innovations in health care
Published: (1990)

Regulations for agricultural products derived from biotechnology
by: 396242 Primary Production Department Singapore
Published: (1998)

Applications of biotechnology with a review molecular biology /
by: Ali Mahmoudpour, author
Published: (2002)

Molecular biology and biotechnology : basic experimental protocols /
by: Bansal, M. P. 536209
Published: (2013)

Molecular biology and biotechnology /
by: Walker, John M., et al.
Published: (2009)

Molecular biology and biotechnology /
by: Rapley, Ralph, editor, et al.
Published: (2015)

Molecular biology and biotechnology /
by: Walker, J. M., et al.
Published: (2000)

Molecular biology and biotechnology : a guide for students /
by: 198786 Kreuzer, Helen, et al.
Published: (2008)

Molecular biology and biotechnology /
by: Walker, J. M., et al.
Published: (1993)

A review on bioconversion of paddy husk into biodiesel / Nur Aqilah Daud
by: Daud, Nur Aqilah
Published: (2017)

Molecular biology and biotechnology : a comprehensive desk reference /
by: 442955 Meyers, Robert A.
Published: (1995)

The molecular basis of substrate specificity in FMN-dependent 2-hydroxyacid dehydrogenases : comparison of the flavocytochromes b2 from rhodotorula graminis and saccharomyces cerevisiae /
by: Rosli Md. Illias, et al.
Published: (2000)

Encyclopaedia of molecular biology /
by: 258951 Prakash, M.
Published: (2007)

Biology for engineers /
by: Johnson, Arthur T. (Arthur Thomas), 1941-
Published: (2011)

Biodiversity, biotechnology, and business /
by: 449206 Mannion, Antoinette M.

Derwent biotechnology abstracts [cakera padat]
Published: (1994)

Cytotoxic Evaluation of <i>Eurycoma longifolia</i> Jack Root Extract on Chromosome Aberrations in Human Lymphocytes <i>In vitro</i>
by: Somkid Chaiphech, et al.
Published: (2022-06-01)

A Small RNA That Neutralizes a Protein Linked to Tumor Development
Published: (2005-01-01)

Neutralizing Aptamers from Whole-Cell SELEX Inhibit the RET Receptor Tyrosine Kinase
by: Cerchia Laura, et al.
Published: (2005-01-01)

Applications of CRISPR/Cas to Improve Crop Disease Resistance: Beyond Inactivation of Susceptibility Factors
by: Dirk Schenke, et al.
Published: (2020-09-01)

Mitigating tradeoffs in plant breeding
by: Sangam Lal Dwivedi, et al.
Published: (2021-09-01)

Ultrasound-controlled acidogenic valorization of wastewater for biohydrogen and volatile fatty acids production: Microbial community profiling
by: Omprakash Sarkar, et al.
Published: (2023-04-01)

A novel in vivo system to study coral biomineralization in the starlet sea anemone, Nematostella vectensis
by: Brent Foster, et al.
Published: (2024-03-01)

Optimization of CRISPR-Cas9 system in Eustoma grandiflorum
by: Xueqi Li, et al.
Published: (2024-03-01)

No country for old methods: New tools for studying microproteins
by: Fabiola Valdivia-Francia, et al.
Published: (2024-02-01)

New perspectives for weeds control using autochthonous fungi with selective bioherbicide potential
by: Francisco Wilson Reichert Júnior, et al.
Published: (2019-05-01)

Biotechnology : applying the genetic revolution /
by: 453699 Clark, David P., et al.
Published: (2009)

Remus: System for remote deep brain interventions
by: Taylor D. Webb, et al.
Published: (2022-11-01)

Expression of PEI-coated gold nanoparticles carrying exogenous gene in periwinkle mesophyll cells and its practice in huanglongbing research
by: Junzhe Zhang, et al.
Published: (2022-06-01)