MTHFD1 promoter hypermethylation increases the risk of hypertension

MTHFD1 promoter hypermethylation increases the risk of hypertension

Objectives: Methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) plays an essential role in folate-mediated one-carbon metabolism which determines both homocysteine remethylation and de novo thymidylate biosynthesis. Hyperhomocysteinemia is positively associated with essential hypertension. This study...

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Bibliographic Details
Main Authors: Miao Xu, Jialin Li, Xiaomin Chen, Liyuan Han, Li Li, Yahui Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2019-07-01
Series:Clinical and Experimental Hypertension
Subjects:
mthfd1
promoter
hypermethylation
hyperhomocysteinemia
essential hypertension
Online Access:http://dx.doi.org/10.1080/10641963.2018.1501057

Internet

http://dx.doi.org/10.1080/10641963.2018.1501057

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