Non-inflammatory tumor microenvironment of diffuse intrinsic pontine glioma

Non-inflammatory tumor microenvironment of diffuse intrinsic pontine glioma

Abstract Diffuse intrinsic pontine glioma (DIPG) is a universally fatal malignancy of the childhood central nervous system, with a median overall survival of 9–11 months. We have previously shown that primary DIPG tissue contains numerous tumor-associated macrophages, and substantial work has demons...

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Bibliographic Details
Main Authors: Grant L. Lin, Surya Nagaraja, Mariella G. Filbin, Mario L. Suvà, Hannes Vogel, Michelle Monje
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Acta Neuropathologica Communications
Subjects:
Diffuse intrinsic pontine glioma
Tumor-associated macrophage
Tumor-infiltrating lymphocyte
Glioma
Glioblastoma
Immune microenvironment
Online Access:http://link.springer.com/article/10.1186/s40478-018-0553-x

Internet

http://link.springer.com/article/10.1186/s40478-018-0553-x

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