Diflunisal Attenuates Virulence Factor Gene Regulation and Phenotypes in <em>Staphylococcus aureus</em>

Diflunisal Attenuates Virulence Factor Gene Regulation and Phenotypes in <em>Staphylococcus aureus</em>

Virulence factor expression is integral to pathogenicity of <i>Staphylococcus aureus</i>. We previously demonstrated that aspirin, through its major metabolite, salicylic acid (SAL), modulates <i>S. aureus</i> virulence phenotypes in vitro and in vivo. We compared salicylate...

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Bibliographic Details
Main Authors: Liana C. Chan, Mihyun Park, Hong K. Lee, Siyang Chaili, Yan Q. Xiong, Arnold S. Bayer, Richard A. Proctor, Michael R. Yeaman
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Antibiotics
Subjects:
salicylates
diflunisal
virulence
antimicrobial
MRSA
<i>Staphylococcus aureus</i>
Online Access:https://www.mdpi.com/2079-6382/12/5/902

Internet

https://www.mdpi.com/2079-6382/12/5/902

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