Causality of telomere length associated with calcific aortic valvular stenosis: A Mendelian randomization study

Causality of telomere length associated with calcific aortic valvular stenosis: A Mendelian randomization study

BackgroundObservational studies have shown that calcific aortic valve stenosis (CAVS) is associated with a shorter telomere length (TL). However, the results of observational studies are often influenced by confounding factors and reverse causal associations; it is unclear whether there is a causal...

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Bibliographic Details
Main Authors: Junkui Wang, Yan Hao, Zhanfang Zhu, Bo Liu, Xuejun Zhang, Na Wei, Ting Wang, Ying Lv, Cuixiang Xu, Meijuan Ma, Yulian Zhang, Fuqiang Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Medicine
Subjects:
telomere length
calcific aortic valve stenosis
genome-wide association study
Mendelian randomization
single nucleotide polymorphism
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.1077686/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.1077686/full

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