Identification of α-Amyrin 28-Carboxylase and Glycosyltransferase From Ilex asprella and Production of Ursolic Acid 28-O-β-D-Glucopyranoside in Engineered Yeast

Identification of α-Amyrin 28-Carboxylase and Glycosyltransferase From Ilex asprella and Production of Ursolic Acid 28-O-β-D-Glucopyranoside in Engineered Yeast

Ilex asprella is a medicinal plant that is used extensively in southern China. The plant contains ursane-type triterpenoids and triterpenoid saponins which are known to be responsible for its pharmacological activities. Previously, a transcriptomic analysis of I. asprella was carried out and the gen...

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Bibliographic Details
Main Authors: Xiaoyu Ji, Shumin Lin, Yuanyuan Chen, Jiawei Liu, Xiaoyun Yun, Tiancheng Wang, Jialiang Qin, Chaoquan Luo, Kui Wang, Zhongxiang Zhao, Ruoting Zhan, Hui Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Plant Science
Subjects:
Ilex asprella
Triterpenoid saponins
Biosynthesis
CYP
UGT
Online Access:https://www.frontiersin.org/article/10.3389/fpls.2020.00612/full

Internet

https://www.frontiersin.org/article/10.3389/fpls.2020.00612/full

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