TOB1 modulates neutrophil phenotypes to influence gastric cancer progression and immunotherapy efficacy

TOB1 modulates neutrophil phenotypes to influence gastric cancer progression and immunotherapy efficacy

IntroductionThe ErbB-2.1(TOB1) signaling transducer protein is a tumor-suppressive protein that actively suppresses the malignant phenotype of gastric cancer cells. Yet, TOB1 negatively regulates the activation and growth of different immune cells. Understanding the expression and role of TOB1 in th...

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Bibliographic Details
Main Authors: Jinfeng Zhang, Yunlong Li, Jing Chen, Tongtong Huang, Jing Lin, Yilin Pi, Huiting Hao, Dong Wang, Xiao Liang, Songbin Fu, Jingcui Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
TOB1
gastric cancer
neutrophils apoptosis
immunotherapy
immune cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1369087/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1369087/full

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