Antimicrobial peptide temporin derivatives inhibit biofilm formation and virulence factor expression of Streptococcus mutans

Antimicrobial peptide temporin derivatives inhibit biofilm formation and virulence factor expression of Streptococcus mutans

IntroductionTemporin-GHa obtained from the frog Hylarana guentheri showed bactericidal efficacy against Streptococcus mutans. To enhance its antibacterial activity, the derived peptides GHaR and GHa11R were designed, and their antibacterial performance, antibiofilm efficacy and potential in the inhi...

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Bibliographic Details
Main Authors: Shangjun Jiang, Yanmei Zha, Ting Zhao, Xiao Jin, Ruiying Zhu, Shuangshuang Wei, Rong Wang, Yanting Song, Lushuang Li, Junchen Lyu, Wenting Hu, Daqi Zhang, Manchuriga Wang, Yingxia Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Microbiology
Subjects:
antimicrobial peptides
temporin
Streptococcus mutans
antibiofilm
anti-caries
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1267389/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2023.1267389/full

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