P- 77 EPIGENOME OF PATIENTS WITH LIVER FIBROSIS, WITH SUSTAINED VIRAL RESPONSE TO HCV IN LIVER BIOPSY AND LIQUID BIOPSY REVEALS THE ASSOCIATION OF DNA METHYLATION AND miRNA EXPRESSION WITH THE DEGREE OF SEVERITY
Introduction and Objectives: It has been shown that DNA methylation patterns and miRNA levels are effective markers for distinguishing different stages of liver fibrosis in European patients. A liquid biopsy allows the evaluation of ccfDNA methylation levels from hepatocytes damaged by necrosis/apop...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-03-01
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Series: | Annals of Hepatology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1665268123000765 |