Enhancing Mesenchymal Stromal Cell Potency: Inflammatory Licensing via Mechanotransduction

Enhancing Mesenchymal Stromal Cell Potency: Inflammatory Licensing via Mechanotransduction

Mesenchymal stromal cells (MSC) undergo functional maturation upon their migration from bone marrow and introduction to a site of injury. This inflammatory licensing leads to heightened immune regulation via cell-to-cell interaction and the secretion of immunomodulatory molecules, such as anti-infla...

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Bibliographic Details
Main Authors: Max A. Skibber, Scott D. Olson, Karthik S. Prabhakara, Brijesh S. Gill, Charles S. Cox
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
mesenchymal stem cell
mechanotranduction
bioreactor
immunomodulation
inflammatory licensing
wall shear stress
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.874698/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.874698/full

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