A requirement for astrocyte IP3R2 signaling for whisker experience-dependent depression and homeostatic upregulation in the mouse barrel cortex

A requirement for astrocyte IP3R2 signaling for whisker experience-dependent depression and homeostatic upregulation in the mouse barrel cortex

Changes to sensory experience result in plasticity of synapses in the cortex. This experience-dependent plasticity (EDP) is a fundamental property of the brain. Yet, while much is known about neuronal roles in EDP, very little is known about the role of astrocytes. To address this issue, we used the...

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Bibliographic Details
Main Authors: John B. Butcher, Robert E. Sims, Neville M. Ngum, Amjad H. Bazzari, Stuart I. Jenkins, Marianne King, Eric J. Hill, David A. Nagel, Kevin Fox, H. Rheinallt Parri, Stanislaw Glazewski
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Hebbian plasticity
homeostatic plasticity
synaptic plasticity
LTD (long term depression)
LTP (long term potentiation)
BCM
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2022.905285/full

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https://www.frontiersin.org/articles/10.3389/fncel.2022.905285/full

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