Single-cell evaluation reveals shifts in the tumor-immune niches that shape and maintain aggressive lesions in the breast
The classification of breast lesions as indolent or aggressive to tailor treatment is crucial. Here, the authors use single-cell transcriptomics and multiparametric imaging of a breast cancer mouse model, report distinct tumor-immune features for the two types of lesions, and suggest the role of IL-...
Main Authors: | , , , , , , , , , , , |
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格式: | Article |
語言: | English |
出版: |
Nature Portfolio
2021-08-01
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叢編: | Nature Communications |
在線閱讀: | https://doi.org/10.1038/s41467-021-25240-z |