In silico approach to design new cyclooxygenase-2 (COX-2) inhibitors based on MM/QM and ADMET analysis

In spite of the availability of inhibitors targeting the Cyclooxygenase-2 (COX-2) enzyme, there persists a need for current medications, not solely within the realm of non-steroidal anti-inflammatory drugs (NSAIDs) but also in diverse therapeutic domains such as cancer prevention and Alzheimer'...

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Bibliographic Details
Main Authors: Ashutosh Kharwar, Akanksha Mishra, Vijay Kumar Singh, Anjani Kumar Tiwari
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Chemical Physics Impact
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667022424000537